
Shiitake mushroom is an adaptogenic mushroom that has been used as a herb in Chinese medicine and cooking for thousands of years. Revered in Japan as the “Elixir of Life”, the shiitake mushroom is celebrated for its regenerative and protective power.

Shiitake mushroom extract strengthens the skin’s own defense and repair mechanisms, promoting enduring vitality and radiance – the essence of juicy, resilient skin.
Djusie uses a titrated shiitake extract, standardized for its lentinan and β-glucan content – ensuring consistent bioactivity and clinically proven efficacy in activating the skin’s immune system.
As we age, or under UV and environmental stress, the skin’s immune system weakens. Lentinan, a natural polysaccharide composed of βD-1,3 and βD-1,6 glucans, reactivates Langerhans cells, keratinocytes, and macrophages, triggering the skin’s natural immune defense. It stimulates interleukin-1 (IL-1) production, enhancing cell communication and protecting against inflammation and premature ageing.
The shiitake extract used in Djusie’s products is titrated with a precisely standardized composition: it contains 2% lentinan and 0.5–4.5% β-glucans, along with 38% essential amino acids and trace elements such as copper, iron, magnesium, manganese, and zinc. It is also a natural source of vitamins B1 and B2, as well as provitamin D2, which support the skin’s metabolism and vitality.
This multi-active composition reinforces the skin’s natural defense system, helping to protect it from premature ageing and oxidative stress. It calms sensitivity, restores balance, and promotes regeneration and resilience, leaving the skin stronger, healthier, and more luminous over time.